Andrew Ewing

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andrewe @ chalmers.se

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Bio
PhD on Quantitative and Qualitative In Vivo Electrochemistry, Analytical and Biological Chemistry, Indiana University

Present and previous positions and periods of appointment

1984-1992 Assistant/Associate Professor, Penn State University
1990-1995 Assistant Head of Department, Director of Graduate Education, Penn State
1992-2010 Professor of Chemistry, Penn State University
1995-2003 Adjunct Professor of Neuroscience and Anatomy, Penn State University
1996-2000 Co-Director, Neuroscience Option, Integrative Biosciences Graduate Program
1999-2010 J. Lloyd Huck Chair in Natural Sciences, Penn State University
1999-2004 Head, Department of Chemistry, Penn State University
2003-2010 Professor of Neural and Behavioral Sciences, Penn State University
2007-2010 Marie Curie Chair, Dept. of Chemistry, University of Gothenburg
2010- Professor of Analytical Chemistry, University of Gothenburg
2010- Adjunct Professor, Department of Chemistry, Penn State University
2011- Chair, Analytical Chemistry, Chalmers University of Technology
2011- Director, Joint Chalmers-GU Initiative for Bioanalytical Chemistry

Research
Electrochemical, separations, imaging with optical and mass spectrometry methods aimed at understanding the chemistry of single nerve cells, single vesicles, neural communication in cell networks and in the Drosophila nervous system; and understanding molecular messengers in cell differentiation. Analytical chemistry methods at the micro- and nanoscale.

Latest Publications

263. Mass spectrometry imaging of freeze-dried membrane phospholipids of dividing Tetrahymena pyriformis, I. Lanekoff, N. T. N. Phan, C. T. Van Bell, N. Winograd, P.Sjövall, and A. G. Ewing, Appl. Surf. Science, 45 (2013) 210-214, DOI: 10.1002/sia.5017.

264. C60-SIMS Studies of Glycerophospholipid in a LIPID MAPS Model Cell Line: KDO2-Lipid A Stimulated RAW 264.7 Cells, M. K. Passarelli, A. G. Ewing, N. Winograd, Appl. Surf. Science, 45 (2013) 298-301.

265. C60-ToF SIMS imaging of frozen hydrated HeLa cells, A. M. Piwowar, S. Keskin, M. O. Delgado, K. Shen, J. J. Hue, I. Lanekoff, A. G. Ewing and N. Winograd, Appl. Surf. Science, 45 (2013) 302-304, DOI: 10.1002/sia.4882.

266. Single Cell Lipidomics: Characterizing and Imaging Lipids on the Surface of Individual Aplysia Californica Neurons with Cluster SIMS, M. K. Passarelli, A. G. Ewing, and N. Winograd, Anal. Chem., 85 (2103) 2231–2238, DOI: 10.1021/ac303038j.

267. Synaptic Dopamine Vesicular Content In Vivo: Insights from Individual Vesicle Analysis, D. M. Omiatek, A. J. Bressler, A-S. Cans, A. M. Andrews, M. L. Heien, and A. G. Ewing, Nature Scientific Reports, 3 (2013) Article no. 1447, doi:10.1038/srep01447

268. Oral Administration of Methylphenidate Blocks the Effect of Cocaine on Uptake at the Drosophila Dopamine Transporter, E. C. Berglund, M. A. Pond, J. D. Keighron, N. T. N. Phan, M. L. Heien, A. G. Ewing, ACS Chem. Neurosci., webprint, DOI: 10.1021/cn3002009.

269. Freeze-Drying as Sample Preparation for Micellar Electrokinetic Capillary Chromatography– Electrochemical Detection Separations of Neurochemicals in Drosophila Brains, E. C. Berglund, N. J. Kuklinski, E. Karagündüz, K. Ucar, J. Hanrieder, A. G. Ewing, Anal. Chem.,85 (2103) 2841–2846, DOI: 10.1021/ac303377x.

270. Imaging Mass Spectrometry in Neuroscience, J. Hanrieder, N. T. N. Phan, M. E. Kurczy, A. G. Ewing, ACS Chemical Neuroscience, web print, DOI: 10.1021/cn400053c.

271. Chemical Analysis of Single Cells, Trouillon, R., M. K. Passarelli, J. Wang, M. E. Kurczy, A. G. Ewing, Anal. Chem., 85 (2013) 522-542, DOI: 10.1021/ac303290s.

272. Individually Adressable Thin-film Ultramicroelectrodes for Spatial Measurements of Single Vesicle Release, J. Wang, R. Trouillon, Y. Lin, M. I. Svensson., A. G. Ewing Anal. Chem., 85 (2013) 5600-5608, DOI: 10.1021/ac4009385.

273. Carbon Nanotube Fiber Microelectrodes Show a Higher Resistance to Dopamine Fouling, W. Harreither, R. Trouillon, P. Poulin, W. Neri, A. G. Ewing, G. Safina, Anal. Chem., 2013, 85 (15) 7447–7453. DOI: 10.1021/ac401399s.

274.    Evaluating the Diffusion Coefficient of Dopamine at the Cell Surface During Amperometric Detection: Disk vs Ring Microelectrodes, R. Trouillon, Y. Lin, L. J. Mellander, J. D. Keighron, A. G. Ewing, Anal. Chem., 85 (2013) 6421–6428. DOI:10.1021/ac400965d

275.    Single Cell Amperometry Reveals Glycocalyx Hinders the Release of Neurotransmitters During Exocytosis, R. Trouillon, A. G. Ewing, Anal. Chem., 85 (2013) 4822–4828. DOI: 10.1021/ac4008682.

276.    Amperometric Measurements at Cells Support a Role for Dynamin in the Dilation of the Fusion Pore during Exocytosis, R. Trouillon, A. G. Ewing, Chemphyschem. 14 (2013) 2295-301. DOI: 10.1002/cphc.201300319.

277.    Capillary Electrophoresis Mass Spectrometry based Detection of Drugs and Neurotransmitters in Drosophila Brain, N. T. N. Phan, J. Hanrieder, E. C.Berglund, A. G. Ewing, Anal. Chem., 85 (2013) 8448–8454. DOI: 10.1021/ac401920v.