Spatial Neuroproteomics Using Imaging Mass Spectrometry

Check out this review by Jörg Hanrieder, Per Malmberg and Andrew G. Ewing on neuroproteomics in BBA Proteins and Proteomics .

Highlights

•Imaging MS allows for spatial protein and peptide profiling at high molecular specificity.
•Recent developments push the limits in terms of spatial resolution, sensitivity and specificity.
•A concise overview of IMS based approaches for protein and peptide imaging is presented.
•Technical concepts and developments of IMS are discussed.
•Implementations of IMS for biomedical applications in neuroscience are presented.